<span>Navy Veteran to Advocate: A Life-Changing Genetic Testing Journey</span>
March 5, 2025

Navy Veteran to Advocate: A Life-Changing Genetic Testing Journey

Dan "Dry Dock" Shockley served on multiple ships before he retired from his 22-year career in the United States Navy. That’s how he got his nickname, “Dry Dock,” traveling to 22 countries all over the world, docking in places like Singapore, Qatar, and Spain. But after settling into retirement on Oahu, he found himself on a new, unexpected journey.
February 28, 2025

AAN Annual Meeting 2025

Advancing breakthroughs for neurodegenerative diseases requires asking complex questions. Labcorp is proud to present three new abstracts at AAN 2025 on how new blood biomarkers can bring clarity to diagnosis and treatment decisions.
February 18, 2025

Biodistribution Assessment of Lipid Nanoparticle-Mediated mRNA Delivery Using In Vivo Imaging

Cayman Chemical’s LNP development services in partnership with Labcorp utilizes in vivo imaging technology to create a comprehensive LNP screening platform. With this approach, three LNP formulations were assessed in vitro and in vivo for potency of reporter gene expression and differential organ delivery. This comprehensive LNP formulation, characterization, and analysis service can be used to identify candidate LNP formulations with tissue-tropic distribution.
March 4, 2025

Continuous infusion in minipigs via semi-permanent over-the-wire central venous catheters using OrchesTA infusion pumps

IAT Congress 2025 -- Our previous methods for intravenous dosing in minipigs were either placing short-term intravenous cannula into the peripheral (saphenous) vein, which is only suitable for bolus or short infusion, or a vascular access port (VAP), involving surgical cannulation of the femoral vein attached to a subcutaneous port on the trunk with a recovery period of 14 days before the port can be used. Following successful use of semi-permanent over-the-wire central venous catheters for repeat blood sampling in minipigs at Harrogate and Huntingdon, it was proposed to use the model for a 24-hour continuous infusion. This was a refinement from the VAP model, as the simpler procedure involved a much shorter anaesthesia and was possible to do within annex of the animal home area, removing the need for transport to the veterinary theatre. It also avoided the need for surgical placement of the catheter and subsequent recovery period with medication administration. The cannulas were well tolerated by the minipigs.