Author: Patrick McConville, PhD, Chief Scientific Officer / SVP

Poster:

 

Poster: Evaluation of Immunomodulatory Agents in Classically Immunologically “Cold” Cancers Using Syngeneic Mouse Models of Breast and Ovarian Cancer

Introduction and Background

• T cell checkpoint inhibitors have demonstrated significant clinical benefit in immunologically “hot” cancer types like melanoma, kidney, bladder and

POSTER | Anti-mCTLA-4 Treatment Results in Early and Late Immune Response Effects in Murine Model of Colorectal Carcinoma (PDF)

Introduction and Background:

• During pre-clinical research, analysis of the tumor immune response at a single post-treatment timepoint is often standard when therapeutic mechanism of action is investigated.

Poster: ?A Comparative Evaluation of Immunotherapy Responses in Murine Colon Carcinoma"

Introduction and Background

• With the drive in oncology to develop molecules targeting the immune system, there is a need for reliable and well-characterized preclinical models.
• The focus of immuno-oncology drug development has shifted to